Severe Asthma: When Infusion Therapy (Xolair) Becomes an Option
For asthma that inhalers alone can't control, an infusion therapy targeting the underlying allergic response can reduce attacks significantly.
What is severe asthma?
Asthma is a chronic condition in which the airways become inflamed and narrowed, making it harder to breathe. Most people manage it well with inhalers, but a smaller group have severe, persistent asthma that keeps causing frequent flare-ups, ER visits, or oral steroid use even on maximum standard treatment.
In many of these cases, the asthma is driven by an allergic (IgE-mediated) response, meaning the immune system overreacts to common triggers like dust, pollen, or pet dander, fueling ongoing airway inflammation.
How infusion therapy helps
Xolair (omalizumab) is a biologic therapy that works by binding to and blocking IgE, the antibody responsible for driving allergic asthma, reducing the inflammatory cascade that leads to asthma attacks.
It's typically given every two to four weeks, with the dose based on body weight and IgE levels. Many patients see a meaningful drop in flare frequency and, over time, are able to reduce their reliance on oral steroids.
Struggling with severe, hard-to-control asthma?
Ask your pulmonologist whether biologic infusion therapy could be right for you, and let our team handle the infusion side.
Call (551) 336-5580This article is for general educational purposes and is not a substitute for medical advice. Treatment decisions should always be made with your physician based on your individual diagnosis and health history.