CONDITIONS WE TREAT

Thyroid Eye Disease (TED): How TEPEZZA Infusion Therapy Works

TED causes bulging, double vision, and pressure behind the eyes. TEPEZZA is the first infusion therapy built to target the disease itself, not just the symptoms.

Specialty Infusions, Teaneck, NJ · Patient Education · September 16, 2026

What is thyroid eye disease?

Thyroid eye disease (TED) is an autoimmune condition, closely linked to Graves' disease, in which the immune system attacks the muscles and fatty tissue behind the eyes. That causes inflammation and swelling that can lead to bulging eyes (proptosis), double vision, pressure, pain, and redness.

TED can occur whether or not thyroid hormone levels are currently well controlled, which is why it sometimes catches patients off guard even after their thyroid condition itself is being managed.

How infusion therapy helps

TEPEZZA (teprotumumab) was the first FDA-approved treatment built specifically for TED. It works by blocking a receptor (IGF-1R) involved in the inflammatory process driving the eye changes, rather than just addressing symptoms after they appear.

Treatment is a course of eight infusions given every three weeks. Clinical studies have shown significant reductions in eye bulging and double vision, with benefit seen regardless of how long someone has had TED.

Living with thyroid eye disease?

Our physician-led team coordinates TEPEZZA infusion therapy with your endocrinologist or ophthalmologist.

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This article is for general educational purposes and is not a substitute for medical advice. Treatment decisions should always be made with your physician based on your individual diagnosis and health history.